Originally posted on Pro Sports Daily  |  Last updated 7/25/12

SAN FRANCISCO -- The San Diego Padres have had their struggles playing against the San Francisco Giants at AT&T Park.

They changed their luck for one day.

Jesus Guzman hit a pair of home runs and had three RBIs, and Chase Headley also homered, lifting the San Diego Padres to a 6-3 win over the San Francisco Giants on Wednesday afternoon.

Jason Marquis (6-9) pitched 7 1/3 innings gave up three hits, one earned run, walked one, and struck out eight for his third consecutive victory, which avoided a sweep in the three-game series.

"He was outstanding," Padres manager Bud Black said. "The old adage, you're only as good as your next day's starter and he was good. He was really good. He set the tone for the day.

"He was efficient. The breaking ball was good today and the fastball had a nice run to it. He pitched inside effectively to the lefties all day. He was under control of the whole game and pitched outstanding."

In 10 starts for the Padres since he cleared release waivers, Marquis is 4-5 with a 3.48 ERA. He was 2-4 with an 8.47 ERA in seven starts with the Minnesota Twins.

"He's been solid," Black added. "We talked this morning about reliability of starting pitching. And he takes the ball, he does his side sessions and he's done good work. Granted there's a performance component at this level. You've got to pitch good to stay in the rotation but he's pitched fine. He's been given an opportunity to get back in a Major League rotation after Minnesota and he's taken full advantage of it by pitching well."

Much of the reason for his struggles in Minnesota was because he tended to his 7-year old daughter Reese, who was seriously injured in a bicycle accident at the end of spring training. He traveled between Minnesota and his home in New York for several weeks during her recovery.

"I just never had time to work on what I needed to work on with my delivery," Marquis said. "It was an unfortunate family situation with my daughter and my sole focus was on them. Given that opportunity to really work on things once we saw my daughter's health was improving.

"She's doing great now and it that's allowed me to focus on the little things that helped make me into the pitcher that I was for the last 13 years. And the numbers are what they were in Minnesota. I'm not happy about them but you just move on from them and I know I was a better pitcher in there and I was able to find it going home and working on my delivery. Coming here to San Diego and working with (pitching coach Darren) Balsley, he's also been a huge help getting me back."

Huston Street pitched the final four outs for his 17th save.

Tim Lincecum's nightmare season continued. The two-time Cy Young winner (4-11) lasted 4 2/3 innings, gave up seven hits, five earned runs, walked three, struck out eight, issued two wild pitches and hit a batter.

"He ran up some deep counts and it caught up with him, the number of pitches he threw," Giants manager Bruce Bochy said. "That played a part in it but I thought he had good stuff. He came out and looked crisp, had a good fastball going. He was a foot away from getting out of that one inning. His last inning, he elevated a ball to Guzman. More than anything the pitches caught up with him today."

After Lincecum recorded two strikeouts in the top of the first, Headley got the Padres on the board with a home run to deep left-center. In the fourth inning, Lincecum gave up singles to Guzman and John Baker. With two outs, Max Venable hit a low liner to left-center just out of reach of Giants center fielder Angel Pagan, allowing two runs to score.

Guzman hit the decisive blow in the fifth inning, crushing an 89 mph Lincecum fastball to the bleachers in left.

"I think execution of my fastball made the difference early on but it got away from me and I wasn't hitting the spots I needed to," Lincecum said. "My focus was today and trying to get a win. That didn't happen and that little bloop that Venable hit made the difference in the game. A tough play to make in no-man's land and obviously the two-run homer from Guzman. I tried to run the two-seamer in on his hands. It stayed straight and he made me pay for it."

Guzman capped the scoring in the eighth inning with his second home run coming off reliever Brad Penny.

Without Buster Posey or Pablo Sandoval in the starting lineup, the Giants had difficulty generating any offense.

"It was one of the better games I'd seen (Marquis) pitch," Giants second baseman Ryan Theriot said. "I played with Jason for a while in Chicago. He had a great slider going today, a good changeup and location.

"He kept his pitch count down, he got ground balls. The main thing with him and any pitcher is first pitch strikes and getting ahead of hitters. He's been doing it for a long time and he's a good pitcher, competitor, good guy, good player."

In the first, Gregor Blanco singled to right-center. He stole second base, advanced to third on a sacrifice bunt. Blanco scored on a sacrifice fly to left field by Melky Cabera. The Giants would not get another hit until Angel Pagan's double with two outs in the seventh inning.

The Giants got a break in the eighth, scoring two runs. Brandon Belt grounded to short but Everth Cabrera threw the ball in the dirt and it bounced into the dugout allowing Belt to reach second on the two-base throwing error. Joaquin Arias singled to short moving Belt to third base. Marquis uncorked a wild pitch that scored Belt and Arias went to second.

Arias made a mental mistake, trying to advance on a ground ball hit deep in the hole at short By Eli Whiteside. Cabrera had no play to get Whiteside but threw out Arias at third base for the first out of the inning. Nate Schierholtz blooped a single to left, off reliever Joe Thatcher. Blanco grounded to third and Schierholtz was erased at second on the force out. With runners at first and third against Luke Gregorson, Ryan Theriot singled to right-center bringing in the third run of the inning.

With runners at the corners, Padres closer Huston Street was summoned from the bullpen and struck out Melky Cabrera to end the threat.

NOTES: The Giants are 6-15 in Lincecum's 21 starts. Lincecum has a 5.88 ERA, highest among National League qualifying pitchers. ... An MRI confirmed that Sandoval has a left hamstring strain. With an off-day Thursday, Giants manager Bruce Bochy said the team will wait until Friday to decide whether Sandoval needs to be put on the disabled list. ... Brandon Belt was 0-for-16 prior to his double in the ninth inning. ... Cabrera was 0-for-3 ending his hit streak at 11 games. ... San Diego scored five of its runs with two outs. ... Guzman is a former Giant and played in 12 games for San Francisco in 2009.

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