Jim Thome hit his 610th career homer to move into seventh place on the career list and the Baltimore Orioles pounded out a 10-2 victory over the Cleveland Indians on Friday night.
Thome passed Sammy Sosa on the career list with a towering 418-foot shot off Derek Lowe (8-8) to open the fourth inning.
Ryan Flaherty had a three-run homer and Mark Reynolds doubled home two runs in a six-run third for Baltimore, which won its third straight.
Miguel Gonzalez (2-1) gave up seven hits over 6 2-3 innings in his third career start. The right-hander struck out five and is 1-0 with a 2.14 ERA on the road.
Asdrubal Cabrera and Jack Hannahan homered for Cleveland, which has lost six of its last nine.