Wei-Yin Chen scattered seven hits over seven innings and the Baltimore Orioles set a franchise record with their seventh straight victory in Boston, beating the Red Sox 2-1 on Wednesday night.
The Orioles, who knocked Boston out of the postseason on the final night of the regular season last year, have won 12 of the past 15 meetings. They are 5-0 at Fenway Park this season.
Endy Chavez, who had three hits in a series-opening win Tuesday, drove in the go-ahead run with a grounder in the sixth. Boston has lost three straight for the first time since early May.
Chen (5-2) was coming off the worst start of his first major league season, when he allowed five first-inning runs Friday in a loss to Tampa Bay. This time he struck out four, didn't walk anyone and stranded six runners.
Josh Beckett (4-6) was the tough-luck loser, allowing two runs, five hits and striking out five in eight innings. It was the fifth consecutive start he's pitched at least seven innings.