The Astros are expected to announce major changes Monday, including the dismissal of general manager Ed Wade, according to major league sources.
Tal Smith, the team's president of baseball operations, also is expected to leave his current position, possibly by retiring, sources say.
New owner Jim Crane, who officially took over last Tuesday, promised quick decisions on the team's hierarchy, saying his timetable was "right after Thanksgiving."
Crane and new team president George Postolos plan one-on-one meetings with all of the team's top executives starting Monday, sources say.
The future of manager Brad Mills, who is under contract through 2012 with an option for '13, also is uncertain. Mills could be part of the initial housecleaning, or his fate could be decided later by a new GM.
Wade, the team's GM since Sept. 20, 2007, is under contract through '12. Smith has been with the Astros a total of 35 years, the last 17 as club president. His career in baseball spans 54 years.