Colts running back Donald Brown, left guard Joe Reitz and safety Tom Zbikowski are inactive for Sunday's game against Tennessee.
All three were ruled out earlier this week by interim coach Bruce Arians.
Also inactive for the Colts are linebacker Mario Harvey, defensive tackle Kellen Heard, receiver Nathan Palmer and offensive lineman Bradley Sowell.
Tennessee deactivated offensive linemen Daniel Baldridge and Mitch Petrus, defensive tackle DaJohn Harris, receivers Lavelle Hawkins and Damian Williams, linebacker Colin McCarthy and quarterback Rusty Smith.
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