The Atlanta Falcons moved to the brink of clinching a division championship.
Drew Brees and the New Orleans Saints wound up with egg on their faces.
After racing to a 17-0 lead, the Falcons turned to their defense to make it stand up, picking off five of Brees' passes and ending his NFL-record touchdown streak in a 23-13 victory over the Saints on Thursday night.
The Falcons (11-1) will clinch the NFC South with a month to go if Tampa Bay loses at Denver on Sunday. They also dealt a big blow to the Saints (5-7) and their fading playoff hopes.
William Moore had two of the five interceptions, which were the most of Brees' career and came four days after he had two passes picked off and returned for touchdowns in a loss to San Francisco.
Brees had thrown a touchdown pass in 54 consecutive games, breaking Johnny Unitas' long-standing record earlier this season. He had an apparent scoring pass to Darren Sproles late in the first half, but it was nullified by a penalty.