With conviction: Steven Jackson. Jackson has averaged 167 yards per game against the Saints, and exploded with 191 all-purpose yards and 2 scores in their last meeting. New Orleans also allowed 235 yards and 5 rushing TDs to CAR in week 17 last season.
Other Start 'Em: Stevan Ridley. In two games against the Bills last season, Ridley accumulated 204 rushing yards and 3 TDs. Buffalo has allowed 450 total rushing yards over their last three games.
David Wilson. The Cowboys have allowed 5 rushing TDs in the last three weeks and Wilson's slippery hands will be a non-issue against a Dallas defense who only managed to recover 3 fumbles all of last season.
Sleeper: Daryl Richardson. The Cardinals defense has been horrendous against opposing running backs for the past SIX weeks, allowing 160 yards per game.
Tough Bench: DeAngelo Williams. I know everybody is high on Williams with the absence of Jon Stewart. Carolina has an early BYE so Williams owners want to get their value fast and early. Unfortunately, Seattle has only allowed 1 rushing TD in their last 5 games and in DeAngelo's only career appearance against the Seahawks he rushed 6 times for 6 yards and a fumble.
Other Sit 'Em: BenJarvus Green-Ellis. Quite frankly, I think the Bengals will phase the Law Firm out of their game plan before the trade deadline. Additionally, the last running back the Bears allowed more than 6 fantasy points to was Adrian Peterson in week 14 of 2012.
Ryan Mathews. I feel like calling him the biggest draft bust of 2013 doesn't make sense because he was also the biggest draft bust of 2012, team owners just haven't learned their lesson yet. Mathews is not the second coming of LaDainian Tomlinson, and he never will be. The Texans only allowed 11.9 fantasy points per game to running backs in 2012. Expect Mathews to either barely reach double-digits (at best), or break his collarbone in the first quarter.
Bold Bust: C.J. Spiller. I know this one is hard for anyone who drafted him in the first round. While New England's defense has always bee subject to question, the numbers are clearly against Spiller this Sunday. In 6 career games against the Patriots, C.J. has never scored a rushing TD and has turned the ball over 3 times. In last year's season opener, New England's defense held Titans' RB Chris Johnson to a grand-total of 4 rushing yards. Finally, Arian Foster is the only RB to score a regular season TD against NE since Thanksgiving, 2012.