For the fifth game in a row, the Indianapolis Colts have lost. Indy's late-season collapse continued as they allowed 48 points to the San Francisco 49ers on home turf in Week 16's edition of Monday Night Football, the Colts' only primetime game of the season.
Monday Night Football brought grit and pushback from the Indianapolis Colts, even as the result slipped away. On MNF against the San Francisco 49ers, Jonathan Taylor delivered a defining TD, forcing his way up the middle for a one-yard score that cut the deficit to 34–27.
Just a week after one of the Indianapolis Colts' best defensive performances of the season, they have by far their worst showing. The Colts fall to 9-7 on the season and have lost six of their last seven after an embarrassing 48-27 showing against the San Francisco 49ers.
There was one important thing that led to the Indianapolis Colts signing NFL legend Philip Rivers for the rest of the season. During the Monday Night Football broadcast, sideline reporter Laura Rutledge shared the story of how the Colts made the final decision on Rivers.
The Indianapolis Colts are in the middle of a shootout against the San Francisco 49ers, but they've already lost two players to injury in the first half.
All NFL players enter the season with high hopes, but sometimes seasons don't go as hoped. These 20 players have been some of the biggest disappointments early in the 2025 season.
The Indianapolis Colts have lost starting center Tanor Bortolini for the rest of the game against the San Francisco 49ers in a 'gotta have it' battle. Now, backup Danny Pinter has entered the contest as the general of the offensive line.
The San Francisco 49ers (11-4) kept pace in the NFC playoff picture with a 48-27 win over the Indianapolis Colts (8-7), whose once-bright season has taken a dark turn.
The Indianapolis Colts are nearing a massive primetime matchup on Monday Night Football with the white-hot San Francisco 49ers. Essentially, Indy's playoff hopes lie in the balance when the bright lights hit Lucas Oil Stadium.
The Indianapolis Colts have had injuries derail what looked like a promising season. Everyone knows the team lost QB Daniel Jones to a torn right Achilles tendon, but they will also be without both their starting tackles in Week 16 vs.
For years, Thanksgiving belonged to the NFL, but Christmas belonged to the NBA. Occasionally, an NFL game would fall on Christmas, but it was anomalous, even avoided if possible.
After coming out of retirement on Dec. 11, Indianapolis Colts quarterback Philip Rivers will make his second start in a row against the San Francisco 49ers on “Monday Night Football.” The 44-year-old almost pulled out a storybook win in his NFL return against the Seattle Seahawks, but the Colts ultimately fell short in the 18-16 loss.
The Indianapolis Colts announced a series of roster moves on Monday as they head into a must-win matchup against the San Francisco 49ers at Lucas Oil Stadium.
The Indianapolis Colts will be playing for their postseason lives against the San Francisco 49ers on Monday Night Football. Defensive end Kwity Paye can’t wait to get on the field.
The Indianapolis Colts got good and bad news on the injury front this week. The good news is that DeForest Buckner is back from the IR and set to play against his former team, the San Francisco 49ers, in Week 16.
Philip Rivers had plenty of experience playing for Indianapolis Colts head coach Shane Steichen. But even he was shocked when he got a call about returning to the NFL.
The Indianapolis Colts announced they have activated DT DeForest Buckner for tonight’s game against the 49ers, his former team before landing with the Colts. To make room, the Colts waived QB Brett Rypien.
The Indianapolis Colts are still unsure of what direction they will go at quarterback in 2026. With Daniel Jones coming off the Achilles injury and questions surrounding Anthony Richardson, the Colts could turn to a former third-rounder.
A neck injury forced Colts defensive tackle DeForest Buckner to IR on Nov. 7. After a five-game absence, Buckner will return Monday against the 49ers, head coach Shane Steichen announced (via Adam Schefter of ESPN).
Anthony Richardson may not play again in 2025, but he will at least see time on the practice field late in the year. The Colts have designated Richardson for return from injured reserve, Shane Steichen announced on Thursday.