The Indianapolis Colts and San Francisco 49ers will meet in a match-up on Sunday for one of the most anticipated games of Week 3.
49ers head coach Jim Harbaugh tailored his game plans around Andrew Luck while at Stanford, now he must find a way to beat him.
CBS will carry this game which will be featured in most households beginning at 4:25 pm ET (1:25 pm PT) from Candlestick Park in San Francisco, CA.
Avg Points Allowed
The San Francisco 49ers are 10 point favorites against the Indianapolis Colts. The over/under for this game is 46.5 total points.
Both teams are coming off losses in Week 2 but who will get their season righted with a win on Sunday?