San Francisco 49ers: Breaking News, Rumors & Highlights

San Francisco 49ers News / 49ers Webzone / December 22

49ers announce roster moves ahead of showdown vs. Colts

The San Francisco 49ers are just hours away from kickoff against the Indianapolis Colts at Lucas Oil Stadium and have announced their pregame roster moves.

San Francisco 49ers News / NFLTradeRumors.co / December 22

49ers Announce Three Moves For Monday Night

The San Francisco 49ers announced they have activated DE Yetur Gross-Matos from injured reserve. They also elevated CB Eli Apple and LB Eric Kendricks from the practice squad for Monday night’s game against the Colts. Gross-Matos, 27, is a former second-round pick of the Panthers back in 2020.

NFL News / San Francisco 49ers on SI / December 22

49ers Counting on Run Defense Changes vs. Colts

The 49ers are in the playoffs, and the goal shifts to acquiring the highest seed. Three wins to close out the year and they complete an improbable run to the NFC’s 1 seed.

Indianapolis Colts News / Yardbarker Quizzes

The 'Multiple 3-rushing-TD games in a season' quiz

How many of the 55 NFL players to get a hat-trick of rushing touchdowns multiple times in the same season can you name in eight minutes?

NFL News / Field Level Media / December 22

Week 16 MNF: 49ers-Colts Preview, Props, Prediction

Several NFL teams will be watching in earnest when the San Francisco 49ers travel to take on the Indianapolis Colts on Monday night in a game chock full of playoff implications for both conferences to close out Week 16.

NFL News / Yardbarker

The biggest disappointments from the 2025 NFL season

All NFL players enter the season with high hopes, but sometimes seasons don't go as hoped. These 20 players have been some of the biggest disappointments early in the 2025 season.

Kyle Shanahan News / 49ers Webzone / December 22

49ers coach Kyle Shanahan reveals key goal to beat Colts in Week 16

The San Francisco 49ers clinched a playoff berth Sunday after the Pittsburgh Steelers defeated the Detroit Lions. Still, the 49ers have plenty at stake heading into Monday night's Week 16 matchup against the Indianapolis Colts.

San Francisco 49ers News / 49ers Webzone / December 22

Only one 49ers player leads position group in Pro Bowl voting

The NFL Communications staff released the latest voting results for the 2026 Pro Bowl Games, with the AFC and NFC rosters set to be unveiled Tuesday morning.

Robert Saleh News / 49ers Webzone / December 22

49ers' Robert Saleh open to head coaching opportunities, but 'it's not desperation'

There is little doubt that San Francisco 49ers defensive coordinator Robert Saleh will be among the top names to watch when NFL teams begin filling head coaching vacancies during the upcoming offseason.

San Francisco 49ers News / Yardbarker Quizzes

The 'Most 30-touch NFL games' quiz

How many of the 48 players in NFL history with 30 or more touches in at least 10 different games can you name in seven minutes?

Jake Tonges News / San Francisco 49ers on SI / December 22

Why this 49ers' place on the depth chart may not reflect his value

The San Francisco 49ers have finally clarified their stance on Jake Tonges, listing him as the third-string tight end on the depth chart. Tonges became a key contributor in the first half of the season, largely due to George Kittle’s hamstring injury suffered in Week 1.

NFL News / Yardbarker

Looking back at every NFL Christmas Day game

For years, Thanksgiving belonged to the NFL, but Christmas belonged to the NBA. Occasionally, an NFL game would fall on Christmas, but it was anomalous, even avoided if possible.

San Francisco 49ers News / San Francisco 49ers on SI / December 22

Key starters expected to return for San Francisco 49ers in Week 16

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never get completely healthy, it is significant to note that they will potentially be getting three significant contributors back on the defensive side of the football in Week 16 against the Indianapolis Colts.

Mac Jones News / San Francisco 49ers on SI / December 21

Why the 49ers Can’t Afford to Lose Mac Jones in 2026

If the 2025 season has proven anything, it’s that the San Francisco 49ers are extremely fortunate to have two quality quarterbacks on their roster. The 49ers have a 10-4 record, reflecting their strong season.

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NFL News / 49ers Webzone / December 21

49ers clinch spot in NFC playoffs with Detroit loss

The San Francisco 49ers have officially clinched a postseason birth for the 2025 NFC playoffs, thanks to the Pittsburgh Steelers, who defeated the Detroit Lions 29-24 on Sunday.

Deommodore Lenoir News / 49ers Webzone / December 21

49ers CB Deommodore Lenoir denies accusation that he skipped holiday event for special needs kids

According to TMZ Sports, San Francisco 49ers cornerback Deommodore Lenoir is being accused of skipping a charity event for children. The function, which was held on December 15, was a holiday toy drive in which Lenoir was expected to collect toys for children with special needs.

San Francisco 49ers News / 49ers Webzone / December 21

49ers vs. Colts: 5 Key Players to Watch in Indy

For the 29th time in franchise history, the San Francisco 49ers have notched 10-plus wins in a season. Following a rare December bye week, the 49ers posted a 37-24 victory over the Tennessee Titans.

Robert Saleh News / San Francisco 49ers on SI / December 21

Robert Saleh reveals the secret ingredient for the 49ers defense

The San Francisco 49ers defense has been playing above its head all season. They have lost pieces, and while they have struggled at times, they have been good enough to hold a 10-4 record with just three games to play.

San Francisco 49ers News / San Francisco 49ers on SI / December 21

49ers must fix this issue in final three games to secure No. 1 Seed

A small but concerning pattern has emerged in recent weeks when the San Francisco 49ers build leads in games. In Week 15 against the Tennessee Titans, the 49ers surrendered 14 points in the fourth quarter.

San Francisco 49ers News / 49ers Webzone / December 21

49ers Keys to Victory vs. Colts: How San Francisco Can Win in Week 16

As the San Francisco 49ers head into a critical Week 16 matchup against the Indianapolis Colts, the margin for error is slim. With playoff positioning on the line, the 49ers must lean into their identity, execute with discipline, and control the game from start to finish.

NFL News / Yardbarker / December 21

Bears stun Packers, take control of NFC North with miraculous comeback

The first of back-to-back Saturdays with NFL games was capped off with one of the games of the year.

Packers QB Jordan Love knocked out of game vs. Bears with concussion

Caleb Williams' heroics vs. Packers should silence doubters

Lions face an unimaginable scenario

Saints sign kicker with unbelievable NFL journey to three-year deal

Bills signing four-time Pro Bowler after he got waived by division rival

San Francisco 49ers News / Pro Football Rumors / December 20

Kyle Shanahan: Brandon Aiyuk has been 'extremely distant' since injury

The San Francisco 49ers placed wide receiver Brandon Aiyuk on the reserve/left squad list last week, raising significant questions about his future in San Francisco.

49ers stay locked into week-to-week focus as playoff stakes rise

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