Allen produced a performance worthy of future Most Valuable Player Award votes as the Bills opened their new Highmark Stadium with an impressive 41-31 win over the Detroit Lions on Thursday night.
Barstool Sports founder Dave Portnoy declared the Detroit Lions’ Super Bowl window closed Friday after Buffalo beat Detroit 41-31 on Thursday night, saying few NFL teams have risen and fallen so quickly.
Buffalo targeted Rock Ya-Sin and Detroit’s safeties 13 times Thursday night, and the film shows a defense repeatedly dealing with blown assignments, poor positioning and communication problems.
On Thursday, September 17, the Buffalo Bills defeated the Detroit Lions 41-31 in Week 2 in their first home game at Buffalo’s new Highmark Stadium. Buffalo winning isn’t a surprise because they were favored to win the game.
Here is everything Dan Campbell said, following the Detroit Lions 41-31 loss to the Buffalo Bills. Opening statement "Give them credit. Joe Brady had those guys ready to go.
A few trades have rearranged the NFL's backup quarterback ranks, but the dust has mostly settled. From a mix of recent first-round disappointments, aging vets, and young project types, here is how the league's QB2 ranks look for the 2026 season.
In their first big test of the season, the Detroit Lions would fail on Thursday Night Football, falling to the Buffalo Bills 42-31 in a game that was never close. The Lions would go down three scores early, and Buffalo would cruise to their first victory in their newly opened stadium.
With the departure of Ben Johnson a couple of years ago, Dan Campbell’s Detroit Lions have stumbled, and as they lost to the Buffalo Bills on Thursday Night Football (TNF), fans joked that the team’s head coach turned into stand-up comedian Shane Gillis.
Detroit Lions safety Avonte Maddox left Thursday night’s 41-31 loss to the Buffalo Bills with a left foot injury, and head coach Dan Campbell said afterward that the veteran’s exit made him nervous.
The Detroit Lions suffered a crushing primetime defeat in Week 2. Detroit could not hang around with Buffalo, losing 41-31 in a game that felt over after the first quarter.
Here are the snap counts from the Detroit Lions Week 2 road contest against the Buffalo Bills. Tight end Sam LaPorta, who has had a solid start to the 2026 season, played 98 percent of offensive snaps.
The Detroit Lions had an opportunity to make a primetime statement against the Buffalo Bills on Thursday Night Football. Going into Buffalo on a night where the Bills were debuting their new stadium, the Lions were ultimately unable to recover after a slow start that saw Buffalo build a big first-half lead.
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Jack Campbell fought back tears in the visitors’ locker room on Thursday night after the Detroit Lions lost to the Buffalo Bills, 41-31, in the first regular-season game at the new Highmark Stadium.
Detroit got strong performances from Jared Goff, Amon-Ra St. Brown and Jahmyr Gibbs, but Buffalo exposed serious concerns with the secondary, defensive approach and offensive-line depth.
The Buffalo Bills matched the events of Thursday night's pregame festivities by producing numerous fireworks of their own en route to opening their new Highmark Stadium with an impressive 41-31 win over the Detroit Lions.
The Detroit Lions fell to 1-1 on the season when they suffered a 41-31 loss at a Buffalo Bills (2-0) side that opened its new Highmark Stadium on Thursday night.
Josh Allen and the Buffalo Bills punched the Detroit Lions in the mouth Thursday night, and no unit felt it more than the visiting team’s defense at the new Highmark Stadium in Orchard Park.
Aidan Hutchinson didn’t hold back on the defensive quality in the Detroit Lions’ 41-31 loss to the Buffalo Bills on Thursday night. Detroit’s defense has been struggling to contain opponents, conceding 30 to the New Orleans Saints in Week 1 before giving up 41 to the Bills.
The Buffalo Bills opened the new Highmark Stadium on Thursday night with a dominating 41-31 win over the Detroit Lions, improving them to 2-0 on the season.
The Buffalo Bills are officially opening Highmark Stadium on Thursday night against the Detroit Lions, and things got off to a poor start before it even began.
The Detroit Lions announced they signed DL Levi Onwuzurike from the practice squad to the active roster and elevated OT Devin Cochran and C Seth McLaughlin from the practice squad. Onwuzurike, 28, was drafted by the Lions with pick No.
Visiting Buffalo on Thursday night, Detroit will have to start multiple backups along the offensive line. The Lions have ruled out right tackle Blake Miller (knee) and left guard Christian Mahogany (hip) for Week 2.