U.S. Open champion Samantha Stosur faces a difficult road in her first tournament of 2012, with Serena Williams, Australian Open champion Kim Clijsters and former No. 1 Ana Ivanovic on her side of the Brisbane International draw.
Hometown favorite Stosur opens play Monday at Pat Rafter Arena against Anastasiya Yakimova of Belarus.
Williams, who hasn't played since losing the final to Stosur at Flushing Meadows, arrived in Brisbane on Saturday and will play Chanelle Scheepers of South Africa in the first round.
Clijsters and Ivanovic could meet in the second round if they win their opening matches.
Top-seeded Andy Murray will play Mikhail Kukushkin of Kazakhstan in a men's first-round match Tuesday.