Dallas Cowboys cornerback Trevon Diggs sits on the bench after a loss to the San Francisco 49ers in the NFC Wild Card game Kevin Jairaj-Imagn Images

Dallas Cowboys open 2025 season with unflattering honor for Week 1

Originally posted on Dallas Cowboys on SI
By Josh Sanchez | Last updated Sep 2, 2025 6:41 PM ET

In approximately 48 hours, the Dallas Cowboys will be taking the field at Lincoln Financial Field to face the Super Bowl champion Philadelphia Eagles in the first game of the 2025-26 NFL regular season.

Dallas enters the game as a massive underdog against the defending champs, with the line shifting even more in Philly's favor after Dallas traded superstar pass rusher Micah Parsons to the Green Bay Packers.

The Cowboys are heavy underdogs for the Week 1 showdown in the NFC East, and the oddsmakers' lack of faith earned Dallas the unfortunate honor of being the biggest underdog (+8.5) across all opening weekend games.

Dallas is an 8.5-point underdog on the road, while the next biggest point spread is the Tennessee Titans (+7.5) against the Denver Broncos.

While the Eagles are favored by 8.5 points, the over/under for the game is set at 47.5 total points. If you're extra confident in the Cowboys, you can bet on Dallas to win on the moneyline at +340, while Philly sits at -430.

That means a $100 wager on the Cowboys would land you a $340 profit, while you would have to risk $430 for a $100 payday by betting on the Eagles.

A full look at the betting odds and information for Thursday night's game can be seen below, via FanDuel Sportsbook.

Dallas Cowboys at Philadelphia Eagles, Week 1 betting odds & viewing info

Date: Thursday, September 4, 2025
Start Time: 8:20 p.m. ET
Location: Philadelphia, Pennsylvania
Venue: Lincoln Financial Field
TV Info: NBC
Live Stream: Peacock

Betting Odds: Eagles -8.5 | O/U: 47.5 (odds via FanDuel Sportsbook)
Moneyline: Eagles -430, Cowboys +340

Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.