San Francisco 49ers: Breaking News, Rumors & Highlights

Key starters expected to return for San Francisco 49ers in Week 16

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never get completely healthy, it is significant to note that they will potentially be getting three significant contributors back on the defensive side of the football in Week 16 against the Indianapolis Colts.

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Why the 49ers Can’t Afford to Lose Mac Jones in 2026

If the 2025 season has proven anything, it’s that the San Francisco 49ers are extremely fortunate to have two quality quarterbacks on their roster. The 49ers have a 10-4 record, reflecting their strong season.

NFL News / 49ers Webzone / December 21

49ers clinch spot in NFC playoffs with Detroit loss

The San Francisco 49ers have officially clinched a postseason birth for the 2025 NFC playoffs, thanks to the Pittsburgh Steelers, who defeated the Detroit Lions 29-24 on Sunday.

Deommodore Lenoir News / 49ers Webzone / December 21

49ers CB Deommodore Lenoir denies accusation that he skipped holiday event for special needs kids

According to TMZ Sports, San Francisco 49ers cornerback Deommodore Lenoir is being accused of skipping a charity event for children. The function, which was held on December 15, was a holiday toy drive in which Lenoir was expected to collect toys for children with special needs.

Jonathan Taylor News / Yardbarker Quizzes

The 'Multiple 3-rushing-TD games in a season' quiz

How many of the 55 NFL players to get a hat-trick of rushing touchdowns multiple times in the same season can you name in eight minutes?

San Francisco 49ers News / 49ers Webzone / December 21

49ers vs. Colts: 5 Key Players to Watch in Indy

For the 29th time in franchise history, the San Francisco 49ers have notched 10-plus wins in a season. Following a rare December bye week, the 49ers posted a 37-24 victory over the Tennessee Titans.

NFL News / Yardbarker

The biggest disappointments from the 2025 NFL season

All NFL players enter the season with high hopes, but sometimes seasons don't go as hoped. These 20 players have been some of the biggest disappointments early in the 2025 season.

Robert Saleh News / San Francisco 49ers on SI / December 21

Robert Saleh reveals the secret ingredient for the 49ers defense

The San Francisco 49ers defense has been playing above its head all season. They have lost pieces, and while they have struggled at times, they have been good enough to hold a 10-4 record with just three games to play.

San Francisco 49ers News / San Francisco 49ers on SI / December 21

49ers must fix this issue in final three games to secure No. 1 Seed

A small but concerning pattern has emerged in recent weeks when the San Francisco 49ers build leads in games. In Week 15 against the Tennessee Titans, the 49ers surrendered 14 points in the fourth quarter.

San Francisco 49ers News / 49ers Webzone / December 21

49ers Keys to Victory vs. Colts: How San Francisco Can Win in Week 16

As the San Francisco 49ers head into a critical Week 16 matchup against the Indianapolis Colts, the margin for error is slim. With playoff positioning on the line, the 49ers must lean into their identity, execute with discipline, and control the game from start to finish.

Jauan Jennings News / San Francisco 49ers on SI / December 21

One must-start in fantasy football on the San Francisco 49ers

The fantasy football playoffs are among us. Whether you are in a big playoff matchup or looking for a Daily Fantasy win before the season ends, most fantasy gamers are going to want Jauan Jennings in their lineup in Week 16.

Brandon Aiyuk News / 49ers Webzone / December 21

Concern growing around 49ers WR Brandon Aiyuk after reckless video surfaces

San Francisco 49ers wide receiver Brandon Aiyuk has yet to play a snap this season and won't, after the team placed him on the reserve/left squad list.

NFL News / Yardbarker

Looking back at every NFL Christmas Day game

For years, Thanksgiving belonged to the NFL, but Christmas belonged to the NBA. Occasionally, an NFL game would fall on Christmas, but it was anomalous, even avoided if possible.

NFL News / Yardbarker / December 21

Bears stun Packers, take control of NFC North with miraculous comeback

The first of back-to-back Saturdays with NFL games was capped off with one of the games of the year.

Packers QB Jordan Love knocked out of game vs. Bears with concussion

Caleb Williams' heroics vs. Packers should silence doubters

Lions face an unimaginable scenario

Saints sign kicker with unbelievable NFL journey to three-year deal

Bills signing four-time Pro Bowler after he got waived by division rival

Click here to get Yardbarker's Quiz of the Day emailed to you!

The '2004-05 NFL passing leaders' quiz

The 'Most multi-rushing-TD NFL games' quiz

The 'NFL's active TD-catch leaders' quiz

The 'Youngest 40-point NBA games' quiz

Ricky Pearsall News / Athlon Sports / December 20

49ers Announce Ricky Pearsall Development Before Colts Game

Ricky Pearsall played a key role in the San Francisco 49ers' Week 15 win over the Tennessee Titans on Sunday. The 25-year-old wide receiver caught six passes from quarterback Brock Purdy for a game-high 96 yards, helping lead the Niners to a 37-24 victory over the Titans.

San Francisco 49ers News / 49ers Webzone / December 20

49ers vs. Colts final injury report: Ricky Pearsall, Renardo Green ruled out for MNF

The San Francisco 49ers are preparing for their Week 16 contest against the Indianapolis Colts on Monday at Lucas Oil Stadium in Indianapolis, Indiana.

San Francisco 49ers News / San Francisco 49ers on SI / December 20

49ers Will be Without Two Skilled Starters Against Indianapolis

The expected and wise move from the San Francisco 49ers has come to fruition. Kyle Shanahan announced on Saturday at his final Week 16 press conference that the 49ers will be without Ricky Pearsall against the Indianapolis Colts due to a PCL injury.

DeForest Buckner News / San Francisco 49ers on SI / December 20

49ers Make it Clear How They Feel About DeForest Buckner

For the second time since they traded him, the San Francisco 49ers will face DeForest Buckner and the Indianapolis Colts. Or at least, that’s how it is trending.

Nick Martin News / San Francisco 49ers on SI / December 20

49ers Put an End to This Rookie's Season

The 2025 draft class is starting to look disappointing for the San Francisco 49ers. On Saturday, the Niners placed rookie linebacker Nick Martin on the Injured Reserve list due to a concussion.

San Francisco 49ers News / Pro Football Rumors / December 20

Kyle Shanahan: Brandon Aiyuk has been 'extremely distant' since injury

The San Francisco 49ers placed wide receiver Brandon Aiyuk on the reserve/left squad list last week, raising significant questions about his future in San Francisco.

49ers stay locked into week-to-week focus as playoff stakes rise

Five teams with most to play for in NFL Week 16

The 25 best NFL head coaches who never won a Super Bowl

The '2023 NFL AP second-team All-Pro' quiz

San Francisco 49ers News / NFL on ClutchPoints / December 19

49ers nightmare playoff scenario with 3 weeks left in regular season

The San Francisco 49ers are favored in their Monday Night Football game, but head coach Kyle Shanahan isn’t taking the Colts’ aging quarterback for granted.