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Why Isaac Guerendo Could be the 49ers' Breakout Player this Year
Deebo Samuel is gone and Brandon Aiyuk might never be the same after tearing his ACL, MCL and meniscus. Which means the 49ers need someone new to step up and become a factor on offense.
Who Will be the 49ers' Backup Running Back this Year?
The backup running back is an important player on the 49ers. That's because their starter, Christian McCaffrey, gets injured frequently. That's what happened when he played for the Carolina Panthers and it's what happened last season on the 49ers.
San Francisco 49ers News / 49ers Webzone / May 16
ESPN doesn't expect much from 49ers' Jordan James in Year 1
ESPN's Mike Clay evaluated the landscape for rookie NFL running backs, projecting the potential roles of several first-year players. Among them is Jordan James, whom the San Francisco 49ers selected in the fifth round of the draft out of Oregon.
The 'NFL all-time touchdown receptions leaders' quiz
How many of the NFL players with at least 80 touchdown catches in their career can you name in five minutes?
Will the 49ers Trade Running Back Isaac Guerendo this Offseason?
Just a year ago, the 49ers traded up to take Isaac Guerendo in Round 4. Now, he might not make their 53-man roster this year. That's why Pro Football Network lists Guerendo as a surprise trade candidate this offseason.
San Francisco 49ers News / 49ers Webzone / April 23
Isaac Guerendo receives praise from star 49ers teammate
Isaac Guerendo made an impression during his 2024 rookie campaign, averaging five yards per carry while stepping up after injuries depleted the San Francisco 49ers' running back room.
San Francisco 49ers News / San Francisco 49ers on SI / April 12
Will 49ers Running Back Isaac Guerendo Make a Big Leap in 2025?
One of the 49ers' most intriguing rookies last season was Isaac Guerendo. He didn't play a ton -- just 222 offensive snaps to be exact. And that's because he a backup and he was injured at times.
NFL News / NFLTradeRumors.co / April 11
NFC Notes: Isaac Guerendo, Bryce Young, 49ers, Cardinals, Panthers
The 49ers traded RB Jordan Mason, which will open up a backup role for RB Isaac Guerendo. San Francisco HC Kyle Shanahan outlined what he liked about Guerendo from his 2024 performance.
San Francisco 49ers News / San Francisco 49ers on SI / April 2
Large Expectations Loom for 49ers RB Isaac Guerendo in 2025
San Francisco 49ers head coach Kyle Shanahan spoke for slightly over 30 minutes at the NFL owners meeting. During his availability, he gave an interesting answer on the running back position.
College Football News / The 33rd Team / March 1
2025 Dynasty Fantasy Football: Buy Or Sell Combine Hype On Biggest Breakouts
Saturday was the big day at the NFL Combine as the quarterbacks, running backs, and wide receivers worked out in Indianapolis. While several top-end receivers and tight ends didn’t end up performing, there were plenty of standouts from the workouts.
NFL News / NFLTradeRumors.co / January 6
NFC Notes: Isaac Guerendo Injury, Jared Verse, Cardinals, Seahawks
49ers HC Kyle Shanahan said RB Isaac Guerendo’s injury is most likely an MCL sprain and that he will undergo further testing. (Matt Barrows) 49ers WR Jauan Jennings was fined $11,817 for Unnecessary Roughness in Week 17.
San Francisco 49ers News / 49ers Webzone / January 6
MRI reveals 49ers RB Isaac Guerendo suffered MCL, ankle sprains
San Francisco 49ers rookie running back Isaac Guerendo shared positive news on Monday morning, revealing via social media that he avoided a dreaded ACL injury, which would have jeopardized his 2025 season.
San Francisco 49ers News / A to Z Sports / January 6
Injury updates from Christian McCaffrey and Isaac Guerendo offer clarity on 49ers backfield for 2025
Arguably no position on the entire San Francisco 49ers depth chart dealt with as much injury adversity than their running back room. Christian McCaffrey missed most of the year owing to Achilles tendinitis before being sidelined with a knee injury suffered in his fourth game of the season.
San Francisco 49ers News / 49ers Webzone / January 6
49ers RB Isaac Guerendo shares positive injury update
San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was carted off to the locker room for evaluation, raising concerns about the severity of his injury.
San Francisco 49ers News / 49ers Webzone / January 5
49ers fear Isaac Guerendo suffered MCL injury, plus other updates
San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. The rookie was carted off the field, and the team later announced he had sustained knee and ankle injuries, ruling him out for the remainder of the game.
San Francisco 49ers News / The Spun / January 5
49ers Running Back Carted Off Field After Suffering Gruesome Injury
The San Francisco 49ers are playing their final game of this brutal 2024 season and it's ending in largely the same way as it began: With a starting running back getting seriously injured.
NFL News / A to Z Sports / January 5
49ers rookie suffers injury that could have big implications for 2025 on first series against Cardinals
It didn't take long for the final game of a San Francisco 49ers season defined by injury adversity to be marred by yet another injury. In fact, it only took four plays.
San Francisco 49ers News / NFLTradeRumors.co / January 5
49ers RB Isaac Guerendo Suffers Left Knee & Ankle Injury
49ers RB Isaac Guerendo was carted off the field at the start of the final game of the season with a left knee injury that appeared to be serious. San Francisco quickly ruled him out for the remainder of the game with a knee and ankle injury.
San Francisco 49ers News / NFL on ClutchPoints / December 28
49ers’ Isaac Guerendo expected to play vs. Lions despite hamstring, foot injuries
With the San Francisco 49ers looking to play spoiler on Monday Night Football against the Detroit Lions, it appears they’ll have Isaac Guerendo back on the field.
San Francisco 49ers News / NFL on ClutchPoints / December 26
Isaac Guerendo finally gives 49ers positive injury update
The San Francisco 49ers are making a final push to close out a lost season on a strong note. Injuries have decimated the reigning NFC champs. Isaac Guerendo, however, provided a promising update.
San Francisco 49ers News / Field Level Media / December 19
Report: 49ers RB Isaac Guerendo likely out vs. Dolphins
San Francisco 49ers running back Isaac Guerendo is unlikely to play in Sunday's game against the host Miami Dolphins, ESPN reported Thursday. Guerendo is nursing a foot injury sustained in the 49ers' 12-6 loss to the Los Angeles Rams last Thursday.
San Francisco 49ers News / A to Z Sports / December 12
49ers get big news on Isaac Guerendo's status ahead of must-win primetime clash with Rams
Isaac Guerendo sprained his foot in the San Francisco 49ers' Week 14 win over the Chicago Bears last Sunday, but just four days on from that injury, the
San Francisco 49ers News / 49ers Webzone / December 9
49ers rookie Isaac Guerendo optimistic about foot injury
San Francisco 49ers rookie running back Isaac Guerendo remains optimistic about his injury status after exiting Sunday's game against the Chicago Bears with a potential foot sprain.
San Francisco 49ers News / San Francisco 49ers on SI / December 6
Chris Foerster Says the 49ers Have to be Careful with Isaac Guerendo
Isaac Guerendo has started just one game at running back since he was in the fourth grade. Now the 49ers need him to start the final five games of the season.
San Francisco 49ers News / 49ers Webzone / October 29
49ers RB Isaac Guerendo nominated for Pepsi Zero Sugar Rookie of the Week award
San Francisco 49ers running back Isaac Guerendo has been nominated for the Pepsi Zero Sugar Rookie of the Week award after an impressive performance in the 49ers' 30-24 Week 8 victory over the Dallas Cowboys.
San Francisco 49ers News / San Francisco 49ers on SI / October 13
Can Isaac Guerendo Carry the 49ers Run Game if Jordan Mason Misses Time?
The 49ers wouldn't have beaten the Seahawks this past Thursday night without rookie running back Isaac Guerendo. The 49ers had a 20-point lead, but starting running back Jordan Mason left the game with a sprained AC joint in his shoulder.
NFL News / Yardbarker / October 11
'TNF' takeaways: Rookies help 49ers avoid another epic collapse
The San Francisco 49ers avoided another epic collapse, earning a 36-24 victory over the Seattle Seahawks on "Thursday Night Football."
San Francisco 49ers News / A to Z Sports / June 23, 2024
49ers coach sets high expectations for rookie Isaac Guerendo with extremely intriguing comparison
The San Francisco 49ers showed how highly they think of Isaac Guerendo's potential when they traded two fifth-round picks to move up in the fourth round of the 2024 NFL Draft to select him.
San Francisco 49ers News / Pro Football Rumors / May 9, 2024
49ers sign three rookies including second-round CB
Dozens of undoubtedly high-end pens are being put to paper around NFL facilities today, and the 49ers are in on the rookie signing action. San Francisco inked three members of its rookie class Thursday night.
NFL News / Yardbarker / April 30, 2024
Five later-round NFL rookies who could thrive in 2024
Here are five players picked in the third round or later in the 2024 NFL Draft who could make an impact and provide more value than their draft spot suggests.
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