Tulane is joining the Big East as a full member in 2014.
"I would go as far to say as this is a historic day for Tulane University ... the Big East is coming to the Big Easy," school President Scott Cowen said.
East Carolina will also join the rebuilding Big East for football only in 2014, a person familiar with the decision told The Associated Press.
The person spoke on condition of anonymity Tuesday because neither the conference nor the school was prepared to make an official announcement. East Carolina, located in Greenville, N.C., has a news conference scheduled for 5 p.m.
Tulane and East Carolina currently play in Conference USA. They will become the fifth and sixth C-USA schools to join the rebuilding Big East in the last two years.
Rutgers announced last week that it would leave the Big East for the Big Ten. Rutgers would like to join the Big Ten by 2014, along with Maryland, but the Scarlet Knights have left their departure date from the Big East ambiguous.