Andy Pettitte left the New York Yankees' game against Seattle on Thursday night in the fifth inning with an apparent injury.
Trailing 2-1, Pettitte struck out Kyle Seager for the second out of the fifth and reached for his right side.
Yankees manager Joe Girardi went to the mound accompanied by pitching coach Larry Rothschild and a trainer. They spoke with Pettitte for a while, then Pettitte trotted to the dugout and was replaced by Shawn Kelley, a former Seattle pitcher.
Pettitte allowed two runs, four hits and three walks in five innings with five strikeouts. He had been seeking his 250th big league win.