Rookie center Jason Slowey is among the 12 players cut by the San Francisco 49ers to trim their roster to 75.
Slowey, a sixth-round draft pick out of Western Oregon, struggled to make an impact during training camp and was waived Monday.
Also cut: fullback Cameron Bell, outside linebacker Kourtnei Brown, defensive tackles Patrick Butrym and Matthew Masifilo, wide receivers Ben Hannula, Joe Hastings and Brian Tyms, cornerbacks Cory Nelms and Deante' Purvis, tight end Joe Sawyer and kicker Giorgio Tavecchio.
On Friday, the Niners (No. 4 in the AP Pro32) must make another round of cuts to finalize their 53-man roster ahead of the season opener Sept. 9 at Green Bay. San Francisco's final preseason game is Thursday night against the San Diego Chargers at Candlestick Park.