Though the Indianapolis Colts got a lengthy look at what life would be like without Peyton Manning last season, they have to be feeling a whole lot better about their quarterback situation with Andrew Luck under center.
The Chicago Bears, meanwhile, are undoubtedly looking forward to Jay Cutler's return from injury - all the more with Brandon Marshall at his disposal.
Luck makes his highly anticipated debut Sunday at Soldier Field as the Colts take on a Bears team hoping to have eight-time Pro Bowl linebacker Brian Urlacher available.
Selected No. 1 overall in the draft after an outstanding career at Stanford, Luck - arguably the most NFL-ready rookie quarterback since Manning in 1998 - has some big shoes to fill.
For the first time in 15 years, Manning will be wearing a different uniform. The Colts decided to let the four-time MVP go after he missed the entire 2011 season due to a series of neck operations, releasing Manning in March following a storied career in Indianapolis.