San Francisco 49ers defensive end Mykel Williams returned to action Sunday for the first time since suffering an ACL injury last season. He played 23 defensive snaps and eight on special teams, recording two tackles in the 49ers' 32-29 win over the Seattle Seahawks.
San Francisco 49ers wide receiver Deebo Samuel is "going to miss some time" with a significant right hamstring strain, according to coach Kyle Shanahan.
The 49ers are 5-0, but injuries continue to plague the oft-malady-stricken team. San Francisco’s receiving corps, in particular, has absorbed a few blows.
The San Francisco 49ers continued their strong start to the 2026 NFL season with a 32-29 win over the defending Super Bowl champion Seattle Seahawks on Sunday.
A few trades have rearranged the NFL's backup quarterback ranks, but the dust has mostly settled. From a mix of recent first-round disappointments, aging vets, and young project types, here is how the league's QB2 ranks look for the 2026 season.
San Francisco 49ers head coach Kyle Shanahan expressed disappointment Monday after learning that the NFL had suspended linebacker Dre Greenlaw for his role in a sideline altercation during Sunday's win over the Seattle Seahawks.
The San Francisco 49ers remain undefeated after edging the Seattle Seahawks 32-29 in a hard-fought Week 5 matchup at Lumen Field on Sunday. Eddy Piñeiro’s 44-yard field goal with 1:56 remaining secured the victory, helping San Francisco to a 5-0 start to the 2026 NFL season.
San Francisco 49ers head coach Kyle Shanahan spoke to reporters Monday, one day after the team's 32-29 Week 5 win over the Seattle Seahawks, providing several injury updates.
The San Francisco 49ers lost Deebo Samuel in the third quarter of Sunday’s 32-29 Week 5 win over the Seattle Seahawks after he suffered a hamstring issue.
NFL stars can't play forever, and retirement is coming sooner than later for some of the league's top players. These 25 players could call it quits following the 2026 season.
Each and every season, the San Francisco 49ers seem to deal with more injuries than any other team in the NFL. That trend has continued this season, with the San Francisco wide receiver room constantly suffering injuries week after week.
The San Francisco 49ers will likely be without linebacker Dre Greenlaw when they host the Washington Commanders on Monday, October 19. The NFL suspended Greenlaw for one game without pay for "an act of unsportsmanlike conduct" during Sunday's 32-29 win over the Seattle Seahawks.
The San Francisco 49ers won a thrilling game against the defending Super Bowl champion Seattle Seahawks. However, with such a tough win can come some ups and downs along the way.
The NFL has unsurprisingly taken action against San Francisco 49ers linebacker Dre Greenlaw for his actions during Sunday’s game against the Seattle Seahawks.
San Francisco 49ers linebacker Dre Greenlaw has been suspended without pay for a one game for his sideline headbutt of Seattle linebacker Ernest Jones IV which resulted in his ejection from the team's 32-29 win over the Seahawks on Sunday, the NFL announced on Monday.
After a sideline dustup led to an ejection on Sunday, 49ers linebacker Dre Greenlaw will sit out Week 6. The NFL has suspended Greenlaw one game without pay for headbutting helmetless Seahawks linebacker Ernest Jones IV in Week 5.
The San Francisco 49ers will remain without linebacker Dre Greenlaw, who has been suspended for one game without pay after a sideline altercation during Sunday's 32-29 win over the Seattle Seahawks at Lumen Field.
The San Francisco 49ers are 5-0 to start the season after defeating the Seattle Seahawks 32-29 at Lumen Field. What's more, San Francisco is 3-0 for the division too.
The San Francisco 49ers’ depth at the wide receiver and defensive line position groups has been seriously depleted due to injuries so far this season. While they welcomed back second-year defensive end Mykel Williams on Sunday after he tore his ACL in Week 9 of last season, they’re still thin at both position groups.
The San Francisco 49ers seem to have found an unexpected solution to their defensive line problems. After losing their entire starting defensive front, the team appeared likely to pursue pass rushers before the trade deadline.
San Francisco 49ers wide receiver Mike Evans made it clear that he intends to help his team whenever he is healthy enough to play, even while dealing with a significant injury.
San Francisco 49ers tight end George Kittle heaped praise on his star wide receiver Mike Evans after his big performance in the team’s close win against the Seattle Seahawks.
Dealing with doubters throughout his whole career, San Francisco 49ers quarterback Brock Purdy continues to prove himself as a worthy franchise leader.
OCTOBER 10: As expected, the 49ers officially announced this afternoon that they have activated Williams from the reserve/physically unable to perform list.