For the third season in a row and the umpteenth time since Kyle Shanahan took over as their head coach, the San Francisco 49ers are dealing with a growing rash of injuries.
For the second season in a row, the San Francisco 49ers will be without All-Pro pass rusher Nick Bosa for an extended period of time. After completing practice Wednesday, the 49ers revealed that Bosa sat out due to injury.
The San Francisco 49ers defensive line is going through a lot of changes with all of the injuries they have suffered. It is hard to keep track of who is on the team and who will be starting when the team takes on the Arizona Cardinals in Week 3.
The San Francisco 49ers have played only two games this season, and their injury list already reads like a roll call. The newest addition is star pass rusher Nick Bosa, who strained his calf while warming up ahead of Thursday's practice.
How many of the active NFL players with at least 400 catches in their career can you name in five minutes?
The San Francisco 49ers will once again have to play without superstar pass rusher Nick Bosa. On Thursday, Bosa suffered a calf injury during a high-knee
A few trades have rearranged the NFL's backup quarterback ranks, but the dust has mostly settled. From a mix of recent first-round disappointments, aging vets, and young project types, here is how the league's QB2 ranks look for the 2026 season.
While it seems unlikely that wide receiver Brandin Cooks will move from the practice squad to the active roster ahead of Sunday's game between the San Francisco 49ers and Arizona Cardinals, head coach Kyle Shanahan offered a positive update on the veteran's progress.
San Francisco 49ers head coach Kyle Shanahan spoke to reporters Friday after news broke that defensive end Nick Bosa will miss multiple weeks after suffering a calf injury during Thursday's practice.
The San Francisco 49ers have barely had time to enjoy their 2-0 start before another injury hits their defensive front. After losing several players already this season, San Francisco now has to deal with a potentially lengthy absence of its biggest name up front: Nick Bosa.
The San Francisco 49ers are preparing for their Week 3 contest against the Arizona Cardinals on Sunday at Levi's Stadium in Santa Clara, California. Both teams have released their official injury reports, which are provided below.
NFL stars can't play forever, and retirement is coming sooner than later for some of the league's top players. These 25 players could call it quits following the 2026 season.
The San Francisco 49ers officially ruled out DE Nick Bosa (calf), WR Demarcus Robinson (ankle), DT James Thompson Jr. (ankle), and DE Romello Height (hand)
San Francisco 49ers defensive end Nick Bosa is expected to miss multiple weeks after suffering a calf injury during practice, according to ESPN’s Adam Schefter and NFL Network’s Ian Rapoport.
San Francisco 49ers wide receiver Mike Evans is participating in Friday's practice after missing the first two sessions of the week due to a hip injury.
The San Francisco 49ers have a home test against the Arizona Cardinals on the docket for Sunday that comes amid Nick Bosa injury concerns. The 49ers’ defense has the depth to withstand Bosa’s issues, as well as depth at the quarterback position in the form of Mac Jones, who was mentioned in a possible trade scenario.
The 49ers took down the Miami Dolphins 35–13 in their Week 2 home opener, moving to 2–0 on the season. Brock Purdy had himself a day, the pass rush showed up, and we got another glimpse of what this team might look like as the season unfolds.
Brock Purdy and San Francisco's star-studded offense have received most of the attention, but the work up front has helped the 49ers get off to an undefeated start.
The San Francisco 49ers are unfortunately dealing with several injuries early in the season, and the latest news doesn’t make anything better. Nick Bosa suffered a calf injury in practice during practice, and he’s expected to miss the next few weeks.
If somebody were to be asked who has the highest career passer rating of all time, they might say a legend like Tom Brady or Aaron Rodgers. Others would choose a quarterback with multiple MVP wins in recent history like Lamar Jackson or Patrick Mahomes.
The NFL announced Thursday that it was fining San Francisco 49ers fullback Kyle Juszczyk $14,926 for a celebration that it deemed an “offensive demonstration.” Count NFL legend Rob Gronkowski among the many observers who have an issue with that decision.
The San Francisco 49ers were flying high after impressive back-to-back wins. But the 49ers received a tough break ahead of their home game vs. Arizona this Sunday.
The San Francisco 49ers are looking like possible Super Bowl contenders and quarterback Brock Purdy is finally starting to get recognition from the national media after starting this season in stellar fashion.
San Francisco 49ers fullback Kyle Juszczyk did not send the NFL a refund request. Instead, he left a taped jug on his locker shelf that read “Not Beer” and let the league stare at the label.
On Thursday, San Francisco 49ers general manager John Lynch strongly suggested that he does not want to part ways with backup quarterback Mac Jones before the NFL trade deadline. Can you blame him?
Recent player punishments are as ridiculous as they are hypocritical, and they're also a reminder of the league's reputation of being a place where no fun is allowed.
A rash of quarterback injuries across the league, particularly Jaxson Dart in New York, has spurred another round of trade rumors.
The NFL has at times been called the "No Fun League" by fans for its crackdown on taunting and celebrations. It's latest fine won't do much to dissuade such characterizations.
With Sam Darnold, Jayden Daniels, Jaxson Dart and Caleb Williams all suffering early season injuries, the importance of having a reliable backup has been on full display again.
They'll still err on the side of caution with the former Tampa Bay Buccaneers star.
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