San Francisco 49ers: Breaking News, Rumors & Highlights

49ers’ Trent Williams limited in practice before upcoming Saints game

The San Francisco 49ers head into their Week 2 matchup against the New Orleans Saints facing some significant injury concerns, most notably with All-Pro left tackle Trent Williams and wide receiver Jauan Jennings.

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Mac Jones opens up about his first 49ers start: 'I've been working for this'

Four years after speculation that the San Francisco 49ers might draft him, quarterback Mac Jones is finally preparing to start a game for the Bay Area franchise.

San Francisco 49ers News / Field Level Media / September 12

49ers QB Brock Purdy out; Mac Jones to start vs. Saints

San Francisco 49ers quarterback Brock Purdy did not practice this week while nursing left shoulder and toe ailments, and on Friday he was ruled out of Sunday's game at the New Orleans Saints.

NFL News / San Francisco 49ers on SI / September 12

Why the 49ers have no excuses against the Saints

The San Francisco 49ers are going to go on the road to take on the New Orleans Saints without Brock Purdy, Brandon Aiyuk, and George Kittle on offense.

Jordan Love News / Yardbarker Quizzes

The 'Last 4,000-yard passer by NFL team' quiz

How many of the players to throw for 4,000 yards in a single season most recently for each NFL franchise can you name in five minutes?

NFL News / Yardbarker

The 25 most memorable Monday Night Football moments

Another NFL season means more potentially memorable moments from Monday Night Football. Here are 25 of the most notable to date.

San Francisco 49ers News / 49ers Webzone / September 12

Shanahan on 49ers vs. Saints: Mac Jones 'awesome' in practice; Kendrick Bourne ready for return

San Francisco 49ers head coach Kyle Shanahan spoke with reporters on Friday, providing final updates ahead of Sunday's Week 2 matchup against the New Orleans Saints.

San Francisco 49ers News / 49ers Webzone / September 12

49ers vs. Saints final injury report: Purdy ruled out for Week 2; Jennings, Williams questionable

The San Francisco 49ers are preparing for their Week 2 contest against the New Orleans Saints on Sunday at the Caesars Superdome in New Orleans, Louisiana.

Jauan Jennings News / NFL on ClutchPoints / September 12

49ers’ Jauan Jennings takes huge step toward injury return vs. Saints

The San Francisco 49ers will be without Brock Purdy in Week 2 against the New Orleans Saints, but might be able to avoid another potentially devastating absence.

NFL News / Yardbarker

25 NFL quarterbacks from the 2000s who you already forgot about

As years go by, it's easy to forget some of the players who suited up on the gridiron. While the quarterback is the one position in the NFL that is under

NFL News / CBSSports.com / September 12

NFL Week 2 injury report: 49ers rule out Brock Purdy, Xavier Worthy doubtful for Chiefs

A rundown of final injury reports ahead of Week 2

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San Francisco 49ers News / NFLTradeRumors.co / September 12

49ers Officially Rule Out Brock Purdy, Starting Mac Jones

The San Francisco 49ers officially ruled out QB Brock Purdy as expected for Week 2 due to a toe injury. This, of course, means that Mac Jones will make

NFL News / San Francisco 49ers on SI / September 12

What the 49ers must do to beat the Saints in Week 2

The 49ers limp into New Orleans without their starting quarterback or All-Pro tight end, and their Hall of Fame left tackle out of shape. Good thing they’re playing the Saints, one of the league’s least talented teams.

Jake Moody News / San Francisco 49ers on SI / September 12

Why Jake Moody might succeed with Bears after failing with 49ers

This is heartwarming. Jake Moody, who kicked himself out of a job with the 49ers three years after they spent a third-round pick on him, has signed with the Chicago Bears' practice squad, according to Jordan Schultz.

San Francisco 49ers News / Niners Nation / September 12

Week 2 numbers to know: The Mac Jones to Kendrick Bourne connection has historically been strong

In the 2010s, the San Francisco 49ers and New Orleans Saints were one of the sneaky better rivalries in football. Every time the two teams played, both teams seemed to be playoff-caliber teams, and every game felt like a big-time matchup.

Trent Williams News / San Francisco 49ers on SI / September 12

Why Trent Williams might sit out the 49ers' Week 2 game in New Orleans

While most people have been focused on the injuries of Brock Purdy and George Kittle this week, another player who's arguably more important than those two quietly has missed practice the past two days as well.

George Kittle News / San Francisco 49ers on SI / September 12

How the 49ers will replace George Kittle at tight end while he's out

George Kittle’s hamstring injury in the season opener vs. Seattle is the worst possible start to his 2025 campaign. It's also just not what the San Francisco 49ers needed either.

Christian McCaffrey News / Athlon Sports / September 11

49ers Announce Christian McCaffrey News After Missing Practice on Wednesday

The San Francisco 49ers have found themselves in a tough position yet again after just one game played in the new season. George Kittle has been placed on injured reserve with a hamstring issue, which was followed by Brock Purdy being diagnosed with a turf toe injury that will cost the star quarterback multiple weeks on the sidelines.

San Francisco 49ers News / Yardbarker / September 11

49ers HC makes strong statement on QB amid Brock Purdy worry

49ers HC makes strong statement on backup QB amid Brock Purdy worry

In the same week that San Francisco 49ers head coach Kyle Shanahan had to release punter Jake Moody, the 49ers are set to give another opportunity to a once optimistic first-round pick at quarterback.

49ers will rely on Mac Jones to save season after Brock Purdy injury news

49ers' situation goes from bad to worse with Brock Purdy injury update

49ers GM gets honest about Brock Purdy's brutal injury, being forced to start Mac Jones

NFL players who are going into decline in 2025

Adrian Martinez News / Pro Football Rumors / September 11

Adrian Martinez To Serve As 49ers’ Backup In Week 2; 49ers Exploring QB Options

As the 49ers prepare for at least one game – but quite possibly more – without Brock Purdy available, their quarterback setup will be worth watching closely. Mac Jones is set to handle starting duties, and an internal option will be relied on to back him up.