SANTA CLARA -- Uh oh. Mykel Williams seems to have re-injured his surgically repaired knee during the 49ers' Week 6 win over the Washington Commanders.
The San Francisco 49ers' former first-round pick Mykel Williams made his 2026 debut after tearing his ACL to end his rookie season. Williams only played 36% of the defensive snaps with 23 snaps overall.
San Francisco 49ers defensive end Mykel Williams returned to action Sunday for the first time since suffering an ACL injury last season. He played 23 defensive snaps and eight on special teams, recording two tackles in the 49ers' 32-29 win over the Seattle Seahawks.
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OCTOBER 10: As expected, the 49ers officially announced this afternoon that they have activated Williams from the reserve/physically unable to perform list.
The NFL trade deadline is November 10 at 4 p.m. ET, and several teams have already signaled their intent to sell off. Several prominent players have already been moved, and these 25 could follow.
The San Francisco 49ers announced the following roster moves on Saturday ahead of a big game on Sunday against the Seattle Seahawks. Activated DL Mykel
The San Francisco 49ers released defensive lineman Ogbo Okoronkwo on Friday, clearing a roster spot as the club prepares to bring back a younger piece of its defensive front.
San Francisco 49ers head coach Kyle Shanahan confirmed that second-year defensive lineman Mykel Williams will be activated from the physically unable to perform (PUP) list on Saturday, ahead of the team's Week 5 matchup against the Seattle Seahawks.
The San Francisco 49ers’ defensive line has been thinned by injury for most of the young season, yet the 49ers are still unbeaten and now expect one of their most promising edge rushers back in the lineup.
San Francisco 49ers head coach Kyle Shanahan shared encouraging injury updates on defensive ends Mykel Williams and Nick Bosa during a Thursday interview on Bay Area radio station KNBR as the team prepares to face the Seattle Seahawks in Week 5.
NFL stars can't play forever, and retirement is coming sooner than later for some of the league's top players. These 25 players could call it quits following the 2026 season.
The San Francisco 49ers' former 11th overall pick Mykel Williams tore his ACL once he was starting to get into a groove during his rookie season. Now, Williams is about a week away from returning to the NFL to start his 2026 season.
The San Francisco 49ers may be 4-0 right now, but they have also been ravaged by injuries for a third straight season. In particular, their wide receiver room and their defensive line have been depleted as a result of multiple key players getting hurt.
Second-year San Francisco 49ers defensive lineman Mykel Williams spoke to reporters ahead of Wednesday's practice, saying he's eager to return to the field.
The San Francisco 49ers’ defensive line and wide receiver rooms have been seriously depleted by the old injury bug so far this season. Coming into Week 1, they were already without two key players at both position groups: defensive end Mykel Williams and wide receiver Christian Kirk.
The 49ers have received a rare piece of good news on the injury front. Per CBS Sports’ Matt Zenitz, DE Mykel Williams is expected to play in San Francisco’s key Week 5 matchup with the Seahawks. Williams, a 2025 first-rounder, sustained an ACL tear midway through his rookie season.
As expected, San Francisco 49ers left tackle Trent Williams returned to practice Thursday after suffering a neck stinger Sunday against the Arizona Cardinals.
The San Francisco 49ers are preparing for their Week 4 contest against the Denver Broncos on Sunday at Levi's Stadium in Santa Clara, California. All eyes are on Mike Evans this week after the wide receiver suffered a rib injury in the 49ers' Week 3 win over the Arizona Cardinals.
San Francisco 49ers head coach Kyle Shanahan spoke to reporters ahead of Wednesday's practice, the team's first of the week as it prepares for its Week 4 matchup against the Denver Broncos.
An offseason rule change adjusted the timelines for players on the reserve/PUP list. They are now eligible to practice after two missed games, as opposed to the four-game wait previously in place.
San Francisco’s second-year defensive end Mykel Williams is nearing his return from an ACL injury suffered in 2025. The 49ers have managed a 2-0 start with a banged-up roster that may be getting back to form.
If the San Francisco 49ers are going to not only make the NFL playoffs but also make noise there and even become contenders, they will need at least a couple of their young prospects to pop.
While the San Francisco 49ers were hoping early on that they would have Mykel Williams back for Week 1, that won’t be the case. General manager John Lynch revealed that Williams would be kept on the Physically Unable to Performa list due to the cartilage damage in his surgically repaired knee.
The San Francisco 49ers find themselves preparing for Aaron Donald again by trading for offensive lineman Jarrett Patterson. Yet the franchise is dealing with a notable NFL Injury on the opposite trenches.
49ers’ second-year DE Mykel Williams finished last season in Week 9 after suffering a torn ACL. When speaking to reporters on Tuesday, HC Kyle Shanahan
On the latest edition of "The Las Vegas Raiders Insider Podcast," Raiders insider Hondo Carpenter of Sports Illustrated offered an update on the Eagles-Crosby rumors.
Mykel Williams is the second-year player with the most at stake. The San Francisco 49ers edge rusher is a major question coming back from his injury, according to Jared Dubin of CBS Sports.
The 49ers dealt with a number of major injuries over the course of the 2025 campaign. One of those was the ACL tear suffered by Mykel Williams, and his ability to start next season remains in question.
Through three games, the DE has logged three stuffs. (A stuff is a tackle on a run play for no gain or negative yardage.)
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