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Dylan Cease throws a pitch during the first inning against the Miami Marlins.
Jul 23, 2025; Miami, Florida, USA; San Diego Padres starting pitcher Dylan Cease (84) delivers a pitch against the Miami Marlins during the first inning at loanDepot Park. Sam Navarro-Imagn Images

How to watch the San Diego Padres vs. St. Louis Cardinals: First pitch, TV & streaming details for tonight

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With the MLB season in full swing, the San Diego Padres sit just 5.5 games away from stealing the division lead from the Dodgers. They now face a critical challenge from the St. Louis Cardinals, a team that knows how to upset the masses. With both teams coming off of losses, can the Padres keep their hold on a wild card spot?

How to watch San Diego Padres vs. St. Louis Cardinals game tonight

  • Matchup: San Diego Padres vs. St. Louis Cardinals
  • Date: Thursday, July 24, 2025
  • Time: 7:45 p.m. ET
  • TV Channels: FDSMW and SDPA
  • Live Stream Platform: Hulu + Live TV, with sports add-on (Regional restrictions may apply)
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium

Predictions, odds, and spread for San Diego Padres vs. St. Louis Cardinals

Key Line
San Diego Padres
St. Louis Cardinals
Run Line
+1.5
-1.5
Run Line Odds
-175
+145

Key players you need to watch on the San Diego Padres

  • Manny Machado – Machado led the Padres in 2025 with 18 home runs, a .285 batting average, .346 OBP, .485 SLG, and 61 RBIs, underlining his role as the team's top power and run producer.
  • Fernando Tatis Jr. – Tatis Jr. hit 16 home runs, stole 22 bases, and posted a .262 average and .797 OPS, providing the Padres with a dynamic combination of power and speed.
  • Luis Arraez – Arraez contributed a .285 batting average and was a key table-setter for the Padres in 2025, leading all regulars with 111 hits.

Key players you need to watch on the St. Louis Cardinals

  • Willson Contreras – Willson Contreras leads the St. Louis Cardinals in home runs so far in the 2025 season.
  • Alec Burleson – Alec Burleson is a key contributor for the Cardinals, currently tied for second on the team in home runs in 2025.
  • Lars Nootbaar – Lars Nootbaar is an important hitter for the Cardinals, also tied for second on the team in home runs during the 2025 season.

Key stats for San Diego Padres

TEAM 1
R
AVG
OBP
SLG
OPS
HR
SB
ERA
WHIP
K
BB
OBA
SV
San Diego Padres
407
.245
.314
.374
.688
86
70
3.58
1.23
868
336
.230
35

Key stats for St. Louis Cardinals

TEAM 2
R
AVG
OBP
SLG
OPS
HR
SB
ERA
WHIP
K
BB
OBA
SV
St. Louis Cardinals
461
.252
.321
.393
.714
100
57
4.21
1.29
754
279
.255
24

Who's winning the San Diego Padres vs. St. Louis Cardinals series?

Though the Padres have motivation, the Cardinals have more to lose, with a must-win needed to advance potentially to the wild card. We can expect a close series on both ends, with both teams fighting for a stop in the loss column. Give me the Cardinals to advance in a nail-biter.