Sam Okuayinonu: Breaking News, Rumors & Highlights

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49ers DL Sam Okuayinonu suffered a foot injury in the team’s final practice before flying to Australia for Week 1 against the Rams. Speaking to the media on Monday, 49ers HC Kyle Shanahan said Okuayinonu’s foot already had a plate in it from a while age.

San Francisco 49ers News / Pro Football Rumors / September 7

49ers DE Sam Okuayinonu To Undergo Foot Surgery; 2026 Return Uncertain

Sam Okuayinonu was set to travel with the 49ers to Australia for the opening game of the season until a foot injury suffered in practice changed his and the team’s plans.

San Francisco 49ers News / 49ers Webzone / September 6

49ers Notebook: Sam Okuayinonu injury revealed; Captains announced in Melbourne; Adjusting to time change

The San Francisco 49ers recently placed defensive end Sam Okuayinonu on injured reserve after ruling him out for their Week 1 matchup against the Los Angeles Rams.

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Ranking the quarterback history of every NFL franchise

Quarterback is the most important position for an NFL team. That wasn’t always the case, but it has been the case for, you know, 50 years at this point essentially.

San Francisco 49ers News / Field Level Media / September 6

49ers place DT Sam Okuayinonu (foot) on IR

San Francisco 49ers defensive tackle Sam Okuayinonu will sit out more than just the team's season opener against the Los Angeles Rams on Thursday in Australia.

San Francisco 49ers News / NFLTradeRumors.co / September 5

49ers Placed DE Sam Okuayinonu On IR, Signed DE Khalid Kareem

Per Pro Football Talk, the 49ers placed DE Sam Okuayinonu on injured reserve and officially signed DE Khalid Kareem off the Falcons’ practice squad to replace him.

San Francisco 49ers News / Field Level Media / September 4

49ers DT Sam Okuayinonu out for opener vs. Rams in Australia

San Francisco 49ers defensive tackle Sam Okuayinonu was ruled out Friday for the season opener against the Los Angeles Rams in Melbourne, Australia. Okuayinonu did not accompany the team on its flight to Australia for next Thursday's contest as he continues to work his way back from a foot injury.

San Francisco 49ers News / NFL on ClutchPoints / September 4

49ers’ Week 1 injury report vs. Rams gets downgrade

While the San Francisco 49ers deal with the drudgery of traveling to Australia, they had one player who didn’t make the flight. And the Week 1 injury report versus the Rams got a downgrade, according to a post on X by Matt Maiocco.

San Francisco 49ers News / 49ers Webzone / September 4

49ers pass rusher ruled out for Week 1 vs. Rams

San Francisco 49ers defensive end Sam Okuayinonu did not travel with the team to Australia and was initially listed as "questionable" for the September 10 matchup against the Los Angeles Rams in Melbourne.

San Francisco 49ers News / Viral Sports News / September 3

San Francisco 49ers Receive Bad Injury News Before Week 1

The San Francisco 49ers left for Australia without one of their veteran defensive ends after a lingering foot problem kept him off the team flight. Sam Okuayinonu stayed behind Wednesday as the rest of the roster headed to Melbourne for next week’s season opener against the Los Angeles Rams.

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The greatest return man for every NFL franchise

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San Francisco 49ers News / 49ers Webzone / September 3

49ers pass rusher doesn't travel with team to Australia

The San Francisco 49ers could be without a key depth piece along the defensive line when they face the Los Angeles Rams in Melbourne, Australia, on September 10.

San Francisco 49ers News / San Francisco 49ers on SI / August 19

49ers Veteran Suddenly Trending Toward Starting Role

Sam Okuayinonu is entering his third year with the San Francisco 49ers, and this could end up being his most important season yet. Okuayinonu will hit free agency this year, and he has the chance to see the most snaps of his career.

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San Francisco 49ers News / San Francisco 49ers on SI / April 10

Where Cam Sample Stands on the 49ers Depth Chart After Signing

The San Francisco 49ers added depth with the addition of Cam Sample. While he has only been a rotational player throughout his career, he has been sticking with teams and getting on the field at times, so he may end up playing a role for the team this year.

San Francisco 49ers News / NFLTradeRumors.co / March 18

49ers Re-Sign RFA DE Sam Okuayinonu

49ers DE Sam Okuayinonu officially signed his one-year restricted tender on Wednesday, according to the NFL Transactions wire. The 49ers used the original-round

San Francisco 49ers News / 49ers Webzone / March 11

49ers tender DE Sam Okuayinonu to one-year, $3.546M deal

According to Matt Barrows of The Athletic, the San Francisco 49ers have tendered restricted free agent defensive end Sam Okuayinonu to a one-year, $3.546 million deal.

San Francisco 49ers News / San Francisco 49ers on SI / December 22

Key starters expected to return for San Francisco 49ers in Week 16

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never get completely healthy, it is significant to note that they will potentially be getting three significant contributors back on the defensive side of the football in Week 16 against the Indianapolis Colts.

San Francisco 49ers News / 49ers Webzone / November 26