San Francisco 49ers: Breaking News, Rumors & Highlights

49ers’ Brock Purdy throws 3rd INT as brutal effort vs. Panthers continues

San Francisco 49ers quarterback Brock Purdy had one of the ugliest halves of his NFL career on Monday. Up against the dangerous Carolina Panthers, Purdy struggled to connect with his receivers, as highlighted by not one, not two, but three interceptions in the first half alone of this Monday Night Football matchup at Levi’s Stadium in Santa Clara.

Features

The Morning Bark

The Quiz of the Day

49ers’ Ji’Ayir Brown steals Bryce Young touchdown with end zone INT

It was a tit-for-tat moment for the defenses of the San Francisco 49ers and the Carolina Panthers early in their Monday Night Football showdown. After forcing Carolina to punt to get a chance to add to their 7-0 lead, the 49ers wasted a possession with SF quarterback Brock Purdy throwing an interception on the first play of a drive.

NFL News / NFLTradeRumors.co / November 24

NFC Notes: Brandon Aiyuk, Jaxon Smith-Njigba, 49ers, Rams, Seahawks

49ers 49ers HC Kyle Shanahan said he hasn’t spoken much with WR Brandon Aiyuk, noting that this is the first time a contract has been voided in his 20 years as a coach.

NFL News / 49ers Webzone / November 24

These 7 49ers players are inactive vs. Panthers

The San Francisco 49ers have released the list of inactive players for their Week 12 matchup against the Carolina Panthers. These seven players will not suit up for the game.

San Francisco 49ers News / Yardbarker Quizzes

The 'Most catches by an NFL running back' quiz

How many of the NFL running backs with the most receptions in a season can you name in five minutes?

The '400-touch NFL seasons' quiz

The 'NFL running back receiving leaders' quiz

The '2024 NFL passing TD leaders' quiz

NFL News / San Francisco 49ers on SI / November 24

Three things the 49ers must do to beat the Carolina Panthers

The 49ers have had a wild season in 2025. Key injuries up and down the board, the Brandon Aiyuk saga, and so much more. Through it all, this team is still in a position to make the playoffs, but a win against the Panthers is the only way to keep the momentum moving in their direction.

NFL News / Yardbarker

The most memorable NFL Thanksgiving game performances

The NFL on Thanksgiving has become one of the great American traditions, dating back to 1920. These are some of the most memorable moments and performances from the Turkey Day games.

Matt Gay News / NFLTradeRumors.co / November 24

49ers Elevate Two Players Including K Matt Gay

The San Francisco 49ers have elevated K Matt Gay and LB Jalen Graham from the practice squad to the active roster for Week 12 against the Panthers, per the NFL’s Official Transaction Wire.

Christian McCaffrey News / Athlon Sports / November 24

NFL Announces Christian McCaffrey Cleat Update Before 49ers-Panthers

Christian McCaffrey and the San Francisco 49ers throttled the Arizona Cardinals in Week 11, winning by a score of 41-22. The win moved San Francisco to

NFL News / Field Level Media / November 24

Week 12 MNF: Panthers-49ers Preview, Props, Prediction

Week 12 of the regular season closes with an intriguing matchup between a surprising team seeking a statement road win against a franchise trying to prove it still belongs among the NFL's top tier of contenders.

San Francisco 49ers News / San Francisco 49ers on SI / November 24

Why this 49ers player is back to his best at the most crucial time

The San Francisco 49ers have been plagued with injuries on both sides of the ball all season. It hasn’t derailed their season, as the organization is 7-4, keeping them in the mix for a playoff spot if they maintain their current form.

San Francisco 49ers News / 49ers Webzone / November 24

Glazer on 49ers WR's future: 'It's up to Brandon Aiyuk'

The turbulence between Brandon Aiyuk and the San Francisco 49ers has reached a new level, and according to FOX Sports insider Jay Glazer, the wide receiver's future is in his own hands.

NFL News / Yardbarker

2026 first-round NFL mock draft: Three QBs in the top 10

With the month of September in the books, both the top college prospects and 2026 NFL draft order are coming into focus. Here's a look at our latest first-round NFL mock draft as of October 13, 2025.

NFL Draft intel: Five prospects on the rise — including Ole Miss' Trinidad Chambliss

Preseason evaluations of Garrett Nussmeier, Cade Klubnik were a huge miss for NFL Draft 'experts'

San Francisco 49ers News / 49ers Webzone / November 24

49ers Keys to Victory: How San Francisco Can Take Down the Panthers on MNF

Faithful to the Bay, it's about to go down. The 7-4 49ers host the 6-5 Panthers at Levi's Stadium on Monday Night Football. Both teams look to increase their chances of advancing to the playoffs.

NFL News / San Francisco 49ers on SI / November 24

These are the 49ers' keys to victory against the Carolina Panthers

As the Brandon Aiyuk drama casts a shadow over Levi’s Stadium, the 49ers have an important game to win to make the playoffs. They face a Carolina team much like their own, an ascending offense that has just broken through, and a punchless defense among the league’s worst in blitz rate, pressure rate, and success rate.

Click here to get Yardbarker's Quiz of the Day emailed to you!

The 'Most catches by an NFL running back' quiz

The '2025 NFL draft QB class' quiz

The 'Active 300-passing-yard game leaders' quiz

The '2022 NFL Week 1 starting QBs' quiz

Brandon Aiyuk News / 49ers Webzone / November 23

NFL insider says 49ers WR Brandon Aiyuk close to being cleared to return, 2026 yet to be written

Brandon Aiyuk's journey with the San Francisco 49ers has been unique. From being in Kyle Shanahan's doghouse in 2021 to making it to the penthouse in 2023, only to end up in the outhouse in 2025, Aiyuk's tenure in Santa Clara has been laced with drama.

San Francisco 49ers News / Last Word On Sports / November 22

Four 49ers to Be Thankful For

As Thanksgiving approaches, the San Francisco 49ers have plenty to be thankful for. Despite a wave of injuries on both sides of the ball, the 49ers enter Week 12 with a 7–4 record and sit firmly in the NFC playoff race.

San Francisco 49ers News / Yardbarker / November 22