San Francisco 49ers: Breaking News, Rumors & Highlights

These are the 49ers' keys to victory against the Carolina Panthers

As the Brandon Aiyuk drama casts a shadow over Levi’s Stadium, the 49ers have an important game to win to make the playoffs. They face a Carolina team much like their own, an ascending offense that has just broken through, and a punchless defense among the league’s worst in blitz rate, pressure rate, and success rate.

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49ers vs. Panthers: 5 Key Players to Watch in the Week 12 Matchup

A floundering Arizona Cardinals team is just what the doctor ordered for the San Francisco 49ers to get back on track to a resounding 41-22 victory. After a six-game hiatus, Brock Purdy returned to toss three touchdown passes.

NFL News / NFLTradeRumors.co / November 23

NFC Notes: Mac Jones, Christian McCaffrey, Jaxon Smith-Njigba, 49ers, Seahawks

49ers RB Christian McCaffrey was under the impression that he was going to be traded to the Rams when he was originally dealt to San Francisco by the Panthers.

George Kittle News / San Francisco 49ers on SI / November 23

One matchup the 49ers must dominate against the Panthers

George Kittle is hot, and the run is expected to extend on Monday Night Football against the Carolina Panthers. Thomas Valentine of Pro Football Focus

Philadelphia Eagles News / Yardbarker Quizzes

The 'Active 300-passing-yard game leaders' quiz

How many of the active NFL quarterbacks to rack up at least 300 yards through the air in a game 10 or more times?

The '100-rushing-yard games by NFL QBs' quiz

The 'Super Bowl-winning starting QBs' quiz

The 'Most passing yards in one Super Bowl' quiz

Brandon Aiyuk News / 49ers Webzone / November 23

NFL insider says 49ers WR Brandon Aiyuk close to being cleared to return, 2026 yet to be written

Brandon Aiyuk's journey with the San Francisco 49ers has been unique. From being in Kyle Shanahan's doghouse in 2021 to making it to the penthouse in 2023, only to end up in the outhouse in 2025, Aiyuk's tenure in Santa Clara has been laced with drama.

College Football News / Yardbarker

College players whose NFL draft stock has risen the most this season

NFL draft stock is fluid from the start of the college football season until it concludes. These 20 players have risen up draft boards in 2025 as a result of their strong start to the season.

NFL News / Total Apex Fantasy Sports / November 23

Carolina Panthers vs. San Francisco 49ers Start Em Sit Em Week 12 2025 Fantasy Focus

Both teams erupted offensively a week ago, surprising skeptics and reminding the NFC that neither intends to go quietly for the 49ers and Panthers. Now, under the lights of Monday Night Football, we get a matchup loaded with fantasy juice and breakout potential.

NFL News / San Francisco 49ers on SI / November 23

5 49ers who must step up to beat the Carolina Panthers

The San Francisco 49ers have a big matchup against the Carolina Panthers that will swing the playoff odds in a big way. If the 49ers want to walk out of

Brandon Aiyuk News / NFLTradeRumors.co / November 23

49ers Think Brandon Aiyuk Is Close To Being Physically Cleared To Play

According to Mike Garafolo, the 49ers think WR Brandon Aiyuk is getting close to receiving physical clearance from the medical team to be able to play. Garafolo confirmed the report from the Athletic that San Francisco voided Aiyuk’s guarantees next year for not fulfilling his obligations with meetings and team activities.

NFL News / Yardbarker

2026 first-round NFL mock draft: Three QBs in the top 10

With the month of September in the books, both the top college prospects and 2026 NFL draft order are coming into focus. Here's a look at our latest first-round NFL mock draft as of October 13, 2025.

NFL Draft intel: Five prospects on the rise — including Ole Miss' Trinidad Chambliss

Preseason evaluations of Garrett Nussmeier, Cade Klubnik were a huge miss for NFL Draft 'experts'

Brandon Aiyuk News / 49ers Webzone / November 23

How 49ers exited Brandon Aiyuk's $120M deal: Dead money and salary cap impact

The San Francisco 49ers have voided the 2026 contract guarantees for wide receiver Brandon Aiyuk, laying the foundation for a divorce between the team and its former star receiver at the end of this season.

NFL News / FirstSportz / November 23

Monday Night Football Week 12: Carolina Panthers vs. San Francisco 49ers preview

Brock Purdy is set to play in his first-ever game against the Carolina Panthers, a week after replacing Mac Jones as the San Francisco 49ers’ starting quarterback.

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The '2025 NFL draft QB class' quiz

The 'Active 300-passing-yard game leaders' quiz

The '2022 NFL Week 1 starting QBs' quiz

The 'NFL single-game completions leaders' quiz

San Francisco 49ers News / NFL on ClutchPoints / November 23

Jauan Jennings weighs in on Brandon Aiyuk’s 2026 voided guarantees

The San Francisco 49ers dropped a bombshell on Friday when the team announced it was voiding Brandon Aiyuk’s 2026 guaranteed money. The surprise move came amid reports that the organization had grown frustrated with Aiyuk’s absence from the team.

Kyle Shanahan News / 49ers Webzone / November 22

How a new 49ers kicker could influence Kyle Shanahan's play-calling

The San Francisco 49ers are expected to elevate recently signed kicker Matt Gay from the practice squad for Monday night's matchup against the Carolina Panthers.

San Francisco 49ers News / 49ers Webzone / November 22

49ers' Ricky Pearsall, Trent Williams open up about Brandon Aiyuk amid uncertain future

Ricky Pearsall may now be the San Francisco 49ers' top wide receiver, despite dealing with injuries this season. With the futures of Jauan Jennings and Brandon Aiyuk uncertain, Pearsall could become quarterback Brock Purdy's primary target moving forward.

San Francisco 49ers News / San Francisco 49ers on SI / November 22