Trey Watts rushed for 149 yards, Alex Singleton ran for three scores and Tulsa beat Iowa State 31-17 on Monday in the Liberty Bowl, avenging a season-opening loss to the Cyclones.
Iowa State rallied to beat Tulsa 38-23 on Sept. 1, but the Golden Hurricane put together the comeback in the rematch. Tulsa trailed 17-7 at the end of the first quarter.
The Golden Hurricane (11-3) posted the second 11-win season in school history. Tulsa, which has the smallest enrollment of any Football Bowl Subdivision program, also finished 11-3 in 2008.
Iowa State (6-7) was seeking its second winning season in the last seven years.
Tulsa scored two touchdowns in the first four minutes of the second quarter to pull ahead for good.
Singleton's three scores gave him a school-record 24 touchdown runs this season.